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Related Concept Videos

Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Author Spotlight: Comparative Imaging of Neural Activity in Awake and Freely Moving States
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Advances in neuroimaging.

Martina E Rodie1, Kirsten P Forbes, Keith Muir

  • 1Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK.

Endocrine Development
|September 24, 2014
PubMed
Summary
This summary is machine-generated.

Neuroimaging reveals brain differences in disorders of sex development (DSD). More research is needed to link these neuroanatomical and neurochemical variations to genetic and hormonal factors in DSD patients.

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Area of Science:

  • Neuroscience
  • Endocrinology
  • Genetics

Background:

  • Significant advancements in neuroimaging over two decades.
  • Limited neuroimaging data exists for patients with disorders of sex development (DSD) due to their rarity.
  • Understanding brain structure, function, and chemistry in DSD is crucial.

Purpose of the Study:

  • Review emerging neuroimaging techniques focusing on brain connectivity.
  • Describe sexually dimorphic brain structures and functions.
  • Summarize current knowledge on neuroanatomy and neurochemistry in individuals with DSD.

Main Methods:

  • Review of recent neuroimaging literature.
  • Focus on brain connectivity analysis.
  • Examination of sexual dimorphism in neuroanatomy, neurochemistry, and neurofunction.

Main Results:

  • Sexual dimorphism is evident across neuroanatomy, neurochemistry, and neurofunction.
  • A key challenge is correlating these differences with individual genetic and hormonal environments.
  • Current understanding of DSD neurobiology is incomplete.

Conclusions:

  • Further neuroimaging studies on typical gender differences are essential.
  • Implications of neuroimaging findings for DSD require more investigation.
  • Future research should explore links between gender-specific brain connectivity and brain diseases.