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Propofol infusion syndrome or not? A case report
James H Diaz1, Cory A Roberts2, Josh J Oliver2
1Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA ; School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA.
Ochsner Journal
|September 25, 2014
Summary
Propofol infusion syndrome (PRIS) is a rare but fatal condition. This case highlights the need for better diagnostic criteria for PRIS, especially in critically ill patients.
Area of Science:
- Anesthesiology
- Critical Care Medicine
Background:
- Propofol is a widely used anesthetic and sedative.
- Propofol infusion syndrome (PRIS) is a rare, potentially fatal complication.
- PRIS diagnosis is challenging due to overlapping symptoms with critical illness.
Observation:
- A previously healthy male patient with multiple gunshot wounds developed PRIS.
- The patient's condition was potentially fatal.
Findings:
- PRIS is a diagnosis of exclusion, often masked by comorbidities.
- The true incidence of PRIS is unknown.
- Objective diagnostic criteria for PRIS are lacking.
Implications:
- Improved diagnostic criteria for PRIS are crucial.
- Enhanced vigilance for PRIS in intensive care settings is necessary.
- Further research is needed to understand PRIS incidence and mechanisms.
Keywords:
Acidosisacute kidney injuryhypnotics and sedativesintensive care unitspropofolrhabdomyolysiswounds–gunshot
