Propofol infusion syndrome or not? A case report
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Updated: Oct 23, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
James H Diaz1, Cory A Roberts2, Josh J Oliver2
1Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA ; School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA.
Background:
Propofol is commonly used and well tolerated for induction of general anesthesia and is also used as a sedative in the intensive care unit. However, in rare cases, the agent may cause a fatal condition known as propofol infusion syndrome (PRIS).
Case Report:
We present a case of PRIS that could have been fatal in a previously healthy male patient with multiple gunshot wounds.
Conclusion:
Because patients typically exhibit other potentially fatal comorbidities, PRIS is always a diagnosis of exclusion. The true incidence of PRIS remains unknown, and more objective criteria for its diagnosis need to be established.
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