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Published on: May 1, 2015
Lymphatic filariasis: A view at pathological diversity
Prashant Basavaraj Mahalingashetti1, Ramaswamy Anikode Subramanian1, Sushan Shweta Jayker1
1Department of Pathology, P E S Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India.
Abstract:
Filariasis is traditionally diagnosed following screening of peripheral smear for microfilaria. Clinically lymphatic filariasis mimics the common local diseases. Thus, it is plausible to observe this parasitic infection in histological sections. We encountered three such cases, which displayed diverse patterns of immune response. Presence of both dead and viable worm at the same foci suggests that such immune response could be the result of parasitic death. Histological features such as endothelial injury and granulomatous response attests to the role of Wolbachia bacteria in influencing tissue response.
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