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Updated: Apr 23, 2026

Formulating and Characterizing Lipid Nanoparticles for Gene Delivery using a Microfluidic Mixing Platform
Published on: February 25, 2021
Recent trends of polymer mediated liposomal gene delivery system
Shyamal Kumar Kundu1, Ashish Ranjan Sharma2, Sang-Soo Lee2
1Department of Physics, School of Basic and Applied Sciences, Galgotias University, Greater Noida 203201, India ; Department of Physics, Tokai University, Hiratsuka-Shi, Kanagawa 259-1292, Japan.
Abstract:
Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to depict a portrait about the polymer based liposomal gene delivery systems and their future applications. Herein, we have discussed in detail the characteristics of liposome, importance of polymer for liposome formulation, gene delivery, and future direction of liposome based gene delivery as a whole.
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