Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Clocks and Seasonal Responses02:45

Biological Clocks and Seasonal Responses

35.9K
The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
35.9K
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

3.4K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
3.4K
Epistasis01:39

Epistasis

37.2K
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
37.2K
Position-effect Variegation02:32

Position-effect Variegation

5.6K
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disulfiram Alleviates MTX-Induced Pulmonary Fibrosis by Inhibiting EMT in Type 2 Alveolar Epithelial Cells.

Lung·2024
Same author

Association of Exercise Tolerance with Respiratory Health Outcomes in Mild-to-Moderate Chronic Obstructive Pulmonary Disease.

Annals of the American Thoracic Society·2024
Same author

Gain of bipolar disorder-related lncRNA AP1AR-DT in mice induces depressive and anxiety-like behaviors by reducing Negr1-mediated excitatory synaptic transmission.

BMC medicine·2024
Same author

Gender differences in clinical characteristics and influencing factors of suicide attempts in first-episode and drug-naïve major depressive disorder patients with comorbid metabolic syndrome.

BMC psychiatry·2024
Same author

Numerical modeling and parametric analysis of temperature distribution in soil based on water content variation under radio frequency heating for in-situ thermal remediation.

The Science of the total environment·2024
Same author

Controllable H<sub>2</sub>S supply via membrane contactors for safe and efficient arsenic precipitation from acidic wastewater.

Journal of hazardous materials·2024
Same journal

Construction and implementation of an ICF-based integrated teaching model for genetic disease severity assessment.

Yi chuan = Hereditas·2026
Same journal

Identification and prenatal genetic testing of pathogenic variants in a case of myoclonus-dystonia syndrome.

Yi chuan = Hereditas·2026
Same journal

A novel strategy to enhance precise targeting of the RNA base editor mxABE.

Yi chuan = Hereditas·2026
Same journal

Functional study of the soybean rapid alkalinization factor <i>GmRALF34s</i> in response to saline-alkali stress.

Yi chuan = Hereditas·2026
Same journal

Role of <i>broad</i> in intestinal stem cells of adult <i>Drosophila</i>.

Yi chuan = Hereditas·2026
Same journal

The p53 R267W mutation intervenes p21-mediated cell cycle arrest and promotes proliferation and migration of lung cancer cells.

Yi chuan = Hereditas·2026
See all related articles

Related Experiment Video

Updated: Apr 23, 2026

In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters
07:44

In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters

Published on: July 4, 2018

7.8K

[Research progresses in animal cryptochromes].

Yuancheng Lu1, Xiaohui Wu1

  • 1State Key Laboratory of Genetic Engineering and National Center for International Research of Development and Disease, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200433, China.

Yi Chuan = Hereditas
|September 25, 2014
PubMed
Summary
This summary is machine-generated.

Animal cryptochromes regulate circadian rhythms and have diverse roles. This review covers their cloning, expression, structure, and functions in magnetoreception, immunity, and metabolism.

More Related Videos

Circadian Entrainment of Drosophila Melanogaster
07:12

Circadian Entrainment of Drosophila Melanogaster

Published on: June 3, 2020

5.8K
Analysis of Circadian Photoresponses in Drosophila Using Locomotor Activity
00:08

Analysis of Circadian Photoresponses in Drosophila Using Locomotor Activity

1.5K

Related Experiment Videos

Last Updated: Apr 23, 2026

In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters
07:44

In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters

Published on: July 4, 2018

7.8K
Circadian Entrainment of Drosophila Melanogaster
07:12

Circadian Entrainment of Drosophila Melanogaster

Published on: June 3, 2020

5.8K
Analysis of Circadian Photoresponses in Drosophila Using Locomotor Activity
00:08

Analysis of Circadian Photoresponses in Drosophila Using Locomotor Activity

1.5K

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Chronobiology

Context:

  • Animal cryptochromes are photoreceptors crucial for circadian rhythms.
  • Two types exist: Type I (light-initiated degradation) and Type II (light-independent inhibition).

Purpose:

  • To review recent research progress on animal cryptochromes.
  • Emphasis on cloning, expression, structural, and functional studies.

Summary:

  • Cryptochromes regulate circadian clocks via distinct mechanisms.
  • Emerging roles in immune response, carbohydrate metabolism, and magnetoreception identified.
  • Studies highlight light-induced chemical magnetoreception in organisms like Drosophila.

Impact:

  • Advances understanding of biological magnetoreception.
  • Potential therapeutic applications for diseases like diabetes.
  • Provides a comprehensive overview for researchers in the field.