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Updated: Apr 23, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
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Levetiracetam reduces abnormal network activations in temporal lobe epilepsy

Britta Wandschneider1, Jason Stretton1, Meneka Sidhu1

  • 1From the Department of Clinical and Experimental Epilepsy (B.W., J.S., M.S., M.C., M.S., P.J.T., J.S.D., M.J.K.), UCL Institute of Neurology, London; the MRC Cognition and Brain Science Unit (J.S.), University of Cambridge; the Imaging and Biophysics Department (M.C.), UCL Institute of Child Health, Great Ormond Street Hospital, London, UK; and the MR Research Center (L.R.K.), Semmelweis University, Budapest, Hungary.

Neurology
|September 26, 2014
PubMed
Summary

Levetiracetam (LEV) helps restore normal brain network activity in patients with drug-resistant temporal lobe epilepsy (TLE). This epilepsy medication showed a dose-dependent effect, normalizing functional network deactivations.

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