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[Familial occurrence of leukemia. Cytogenetic considerations apropos of 2 cases]
The authors describe a case of family leukemia: an acute myeloid leukemia preceded by Pelger's anomaly in a 77 year old brother and a chronic myeloid leukemia chromosome Ph + in a 71 years old sister, sixteen years after the first one. The authors formulate a hypothesis that both haematologic diseases may have in common a mistake of transcription caused by an anomalous m RNA.
The authors describe a case of family leukemia: an acute myeloid leukemia preceded by Pelger's anomaly in a 77 year old brother and a chronic myeloid leukemia chromosome Ph + in a 71 years old sister, sixteen years after the first one. The authors formulate a hypothesis that both haematologic diseases may have in common a mistake of transcription caused by an anomalous m RNA.