Related Experiment Video
Updated: Apr 23, 2026

03:51
Author Spotlight: Investigating Wound Healing in Mice Models of Oronasal Fistulas
Published on: September 8, 2023
1.9K
Chronic Ulceration and Sinus Formation due to Foreign Body: An Often-Forgotten Problem
Karin Birgitte Hansen1, Finn Gottrup2
1Hvidovre University Hospital, Copenhagen, Denmark.
The International Journal of Lower Extremity Wounds
|September 27, 2014
Summary
Foreign body reactions to surgical materials can cause persistent sinus formation and secretion. Early diagnosis and removal of the foreign body, often aided by fistulography and ultrasound, are crucial for resolution.
Area of Science:
- Medical Case Reports
- Surgical Complications
- Immunology
Background:
- Foreign bodies, such as suture or mesh remnants, can elicit a foreign body reaction.
- This reaction may manifest as sinus formation, cavity development, chronic secretion, and ulceration.
- Such complications can arise even after seemingly simple surgical procedures.
Observation:
- A case report details a 49-year-old male with a 9-year history of sinus formation stemming from a foreign body reaction.
- The condition was challenging to diagnose, even with advanced imaging techniques.
- Persistent secretion and sinus formation were the primary clinical manifestations.
Findings:
- Foreign body reactions are often overlooked causes of chronic post-surgical complications.
- Fistulography and ultrasound scanning are identified as optimal diagnostic tools for identifying the causative foreign body.
- Complete resolution was achieved by diagnosing and removing the inciting foreign material.
Implications:
- Re-establishing awareness of foreign body reactions within the healthcare system is essential.
- This is particularly important in fields utilizing implanted foreign materials.
- Prompt diagnosis and intervention can prevent prolonged morbidity associated with these reactions.
Related Concept Videos
Peptic Ulcer Disease II: Pathophysiology
36
Peptic ulcer disease develops when protective mechanisms of the gastrointestinal mucosa are overwhelmed by harmful factors, leading to localized erosions in the stomach or proximal duodenum. The main causes are Helicobacter pylori infection and chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs).Helicobacter pylori–Induced InjuryBacterial Adaptation and Colonization:H. pylori is a spiral, Gram-negative bacterium adapted to the acidic stomach. and transmitted through oral-oral or...
36
Peptic Ulcer Disease II: Pathophysiology
2.9K
Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
2.9K
Peptic Ulcer Disease I: Introduction
1.2K
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
1.2K
Peptic Ulcer Disease I: Introduction
21
Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...
21
Chronic Bowel Disorders: Introduction
887
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
887
Chronic Pharyngitis
16.6K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
16.6K
