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The prevalence of systemic autoimmune rheumatic diseases in Canadian pediatric populations: administrative database
Natalie Jane Shiff1, Lisa M Lix, Lawrence Joseph
1Department of Paediatrics, Royal University Hospital, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SK, S7N 0W8, Canada, natalie.shiff@usask.ca.
Insights
Systemic autoimmune rheumatic diseases (SARDs) affect children across Canada, with prevalence varying by province. These conditions are more common in females and urban populations, highlighting the need for targeted healthcare strategies.
Area of Science:
- Rheumatology
- Pediatrics
- Epidemiology
Background:
- Systemic autoimmune rheumatic diseases (SARDs) represent a significant health concern in pediatric populations.
- Accurate prevalence data is crucial for resource allocation and understanding disease burden in children.
Purpose of the Study:
- To estimate the prevalence of SARDs in individuals aged 18 years and younger across four Canadian provinces.
- To identify demographic and geographic variations in pediatric SARD prevalence.
Main Methods:
- Utilized administrative data, including physician billing claims and inpatient hospitalization records.
- Defined pediatric SARD cases based on specific diagnostic codes and healthcare encounter criteria (hospitalization or multiple physician visits).
- Analyzed data from Alberta, Manitoba, Quebec, and Saskatchewan.
Main Results:
- Pediatric SARD prevalence estimates ranged from 15.9 per 100,000 in Quebec to 23.0 per 100,000 in Manitoba.
- SARDs were found to be more prevalent in females compared to males across all studied provinces.
- A slightly higher prevalence was observed in urban areas compared to rural areas in Alberta and Saskatchewan.
Conclusions:
- This study provides essential population-based prevalence estimates for pediatric SARDs in the analyzed Canadian provinces.
- Findings underscore the higher burden of SARDs in females and urban populations, informing public health initiatives.
- Administrative data offers a valuable tool for epidemiological research on rare pediatric diseases.
Abstract:
To estimate systemic autoimmune rheumatic disease (SARD) prevalence using administrative data for pediatric populations in four Canadian provinces. Physician billing claims and inpatient hospitalizations from Alberta, Manitoba, Quebec, and Saskatchewan were used to define cases aged ≤18 years with a SARD diagnosis code in: one or more hospitalization, two or more physician visits within 2 years and at least 2 months apart, or one or more physician visit to a rheumatologist. Estimates ranged from 15.9/100,000 in Quebec [95% confidence interval (95% CI) 14.1, 18.0] to 23.0/100,000 in Manitoba (95% CI 17.9, 29.2). SARDs were more common in females than in males across all provinces. There was a slightly higher prevalence among those living in urban compared to rural areas of Alberta (rate difference 14.4, 95% CI 8.6, 20.1) and Saskatchewan (rate difference 13.8, 95% CI 1.0, 26.6). Our results provide population-based prevalence estimates of pediatric SARDs in four Canadian provinces.
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