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Updated: Jan 28, 2026

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring
Published on: June 13, 2025
Severe epilepsy in an adult with partial trisomy 18q
Luigi del Gaudio1, Salvatore Striano, Antonietta Coppola
1Epilepsy Centre, Neurology Department, Federico II University, Naples, Italy.
Abstract:
Epilepsy is one of the most common presentations associated with chromosome aberrations. Detailed descriptions of some aberration-specific epileptic and electroencephalographic (EEG) phenotypes have been reported (i.e., Angelman syndrome, ring 20 etc.). However there is limited and mixed information about the characteristics of epilepsy related to trisomy 18. Thus a common seizure phenotype has not been characterized yet. Here we describe in detail a patient with refractory epilepsy and partial 18q trisomy.
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