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Prognostic value of normal stress echocardiography in obese patients
Michele Murphy1, Siva Krothapalli1, Jose Cuellar1
1Division of Cardiology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, BBR 6518, Augusta, GA 30912-3105, USA.
Insights
Obese patients with chest pain can safely undergo stress echocardiography. A normal stress echocardiogram effectively identifies obese individuals at low risk for major adverse cardiac events within one year.
Area of Science:
- Cardiology
- Medical Imaging
- Obesity Medicine
Background:
- Chest pain is a frequent complaint among obese individuals.
- Obesity can limit the accuracy of noninvasive cardiac diagnostic tests.
- Evaluating coronary artery disease (CAD) in obese patients presents unique challenges.
Purpose of the Study:
- To assess the utility of stress echocardiography (SE) in obese patients with chest pain.
- To determine the 1-year risk of major adverse cardiac events (MACE) following a normal SE in different BMI categories.
- To establish SE as a reliable noninvasive tool for risk stratification in obese populations.
Main Methods:
- A retrospective analysis of 704 patients who underwent clinically indicated SE.
- Patients were categorized into normal weight, overweight, and obese groups based on BMI.
- Major adverse cardiac events (MACE) were tracked for one year post-SE.
Main Results:
- No MACE were observed within one year in patients with a normal SE, irrespective of BMI.
- The study included 366 obese, 196 overweight, and 142 normal weight individuals.
- Exclusion criteria included abnormal/indeterminate SE and loss to follow-up.
Conclusions:
- Stress echocardiography is a reliable noninvasive method for assessing cardiac risk in obese patients.
- A normal SE indicates a low 1-year risk of cardiac events, even in obese individuals with cardiac risk factors.
- SE aids in identifying obese patients who do not require immediate cardiac intervention.
Background:
Chest pain is a common problem in obese patients. Because of the body habitus, the results of noninvasive evaluation for CAD may be limited in this group.
Methods:
We reviewed the records of 1446 consecutive patients who had undergone clinically indicated stress echocardiography (SE). We compared major adverse cardiac events (MACE; myocardial infarction, cardiac intervention, cardiac death, subsequent hospitalization for cardiac events, and emergency department visits) at 1 year in normal weight, overweight, and obese subjects with normal SE.
Results:
Excluding patients with an abnormal and indeterminate SE and those who were lost to follow-up, a retrospective analysis of 704 patients was performed. There were 366 obese patients (BMI ≥ 30), 196 overweight patients (BMI 25-29.9), and 142 patients with normal BMI (18.5-24.9). There was no MACE in the groups at 1-year follow-up after a normal SE.
Conclusions:
In obese patients including those with multiple risk factors and symptoms concerning for cardiac ischemia, stress echocardiography is an effective and reliable noninvasive tool for identifying those with a low 1-year risk of cardiac events.
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