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Complete sequence of a cholangiocarcinoma inbred Sprague-Dawley rat model mitochondrial genome

Ai-Hua Luo1,2, Gao-Feng Zhang3, Yi-Fa Yin2

  • 1a Department of Radiation & Medical Oncology , Zhongnan Hospital, Wuhan University , Wuhan , P.R. China .

Mitochondrial DNA. Part A, DNA Mapping, Sequencing, and Analysis
|September 27, 2014
PubMed

Keywords:
Cholangiocarcinomagenomemitochondrion

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Animal Mitochondrial Genetics02:59

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Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...