Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

1.0K
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
1.0K
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

1.8K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.8K
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

581
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
581
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

442
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
442
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

1.6K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

838
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
838

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Syncope-Related Gallavardin Tachycardia Detected by an Implantable Monitor in an Elderly Patient : Ablative Management].

Annales de cardiologie et d'angeiologie·2025
Same author

Evolution of non-invasive myocardial work in tako-tsubo cardiomyopathy.

The international journal of cardiovascular imaging·2023
Same author

Annales de cardiologie et d'angeiologie·2021
Same author

[Infectious and inflammatory complications occurring after cardiac surgery in cardiac rehabilitation centres].

Annales de cardiologie et d'angeiologie·2020
Same author

The left atrial function is transiently impaired in Tako-tsubo cardiomyopathy and associated to in-hospital complications: a prospective study using two-dimensional strain.

The international journal of cardiovascular imaging·2019
Same author

[Cardiac rehabilitation in elderly patient].

Annales de cardiologie et d'angeiologie·2018

Related Experiment Video

Updated: Apr 23, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

3.0K

[Coronary microvascular dysfunction and aortic stenosis: an update].

P Meimoun1, D Czitrom2

  • 1Service de cardiologie-USIC, centre hospitalier de Compiègne, 8, rue Henri-Adnot, 60200 Compiègne, France.

Annales De Cardiologie Et D'Angeiologie
|September 28, 2014
PubMed
Summary
This summary is machine-generated.

Coronary microcirculatory impairment is central to aortic stenosis (AS) pathophysiology. This review explores its causes, links to heart changes, and its role in diagnosing and predicting AS outcomes.

Keywords:
Aortic stenosisCoronary flow reserveMicrocirculationRéserve coronaireRétrécissement aortique

More Related Videos

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

14.8K
Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations
08:21

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Published on: July 21, 2023

2.0K

Related Experiment Videos

Last Updated: Apr 23, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

3.0K
Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

14.8K
Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations
08:21

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Published on: July 21, 2023

2.0K

Area of Science:

  • Cardiology
  • Vascular Biology
  • Cardiac Physiology

Context:

  • Aortic stenosis (AS) is a prevalent valvular heart disease requiring surgical intervention.
  • Coronary microcirculatory dysfunction is increasingly recognized in AS pathophysiology.
  • Existing research utilizes diverse methods to assess microcirculatory impairment in AS patients.

Purpose:

  • To review the multifaceted impairment of the coronary microcirculation in aortic stenosis.
  • To elucidate the origins and functional implications of this impairment.
  • To examine the relationship between microcirculatory function, left ventricular hypertrophy, and AS severity.

Summary:

  • Coronary microcirculatory impairment is a significant pathophysiological component of aortic stenosis.
  • Its origins are multifactorial, involving hemodynamic changes and left ventricular hypertrophy.
  • The review synthesizes current knowledge on diagnostic and prognostic implications.

Impact:

  • Highlights the importance of assessing coronary microcirculation in AS management.
  • Provides a comprehensive overview for clinicians and researchers.
  • Underscores potential avenues for improved diagnostic and therapeutic strategies in AS.