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Updated: Apr 23, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
[Practical conduct for patients with a lonely hypoxemia at rest or during exercise]
N Paleiron1, E Riviere1, G Rohel2
1Service des maladies respiratoires, HIA Clermont-Tonnerre, hôpital d'instruction des Armées, BCRM Brest, CC41, rue Colonel-Fonferrier, 29240 Brest cedex 9, France.
Introduction:
Hypoxemia is a decrease in blood oxygen partial pressure. This work aims at presenting a practical conduct for patients with a lonely hypoxemia at rest or during exercise, defined by the absence of dyspnea at rest, obvious clinical or radiographic abnormality.
State Of The Art:
Diagnostic tools available to the clinician are clinical examination, CT scan, echocardiography, hyperoxia test, trans cranial ultrasound and lung scintigraphy. This work proposes a practical diagnostic approach, with a main role of chest CT.
Perspectives:
Work is underway to determine more precisely the place of echocardiography for the diagnosis of intra or extra cardiac shunts.
Conclusions:
The finding of a lonely hypoxemia requires careful diagnostic approach to quickly rule out potentially serious causes and not to disregard the rare causes.
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