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Updated: Apr 23, 2026
06:39
Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
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Postpartum depression and psycho-socio-demographic predictors
Fatemeh Abdollahi1, Shariff-Ghazali Sazlina, Azhar Md Zain
1Department of Public Health, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Summary
Postpartum depression affects one in ten women, persisting for at least 12 weeks. Key predictors include psychological distress during pregnancy and a family history of depression.
Area of Science:
- Obstetrics and Gynecology
- Psychiatry
- Public Health
Background:
- Postpartum depression (PPD) is increasingly recognized as a significant global public health issue.
- Understanding PPD prevalence and predictors is crucial for maternal health initiatives.
Purpose of the Study:
- To determine the prevalence and psycho-socio-demographic predictors of PPD symptomatology.
- To assess the constancy of PPD over a 12-week postpartum period in Iranian women.
Main Methods:
- A cohort of 1,950 pregnant women was assessed at 2 and 12 weeks postpartum.
- The Edinburgh Postnatal Depression Scale and General Health Questionnaire were utilized.
- Logistic regression analysis identified key predictors of PPD.
Main Results:
- A persistent depression rate of 9.9% was observed across assessments.
- Maternal psychological distress, prior depression/anxiety during pregnancy, and family history of depression were strong predictors.
- Early marriage age was also associated with increased PPD risk.
Conclusions:
- Approximately 10% of women experienced ongoing depression 12 weeks postpartum.
- Targeted interventions for high-risk individuals, particularly those with prenatal psychological distress, are recommended.
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