Ultrasonic evaluation of dental implant osseointegration

Dental implants are widely used for oral rehabilitation. However, there remain risks of failure which are difficult to anticipate and depend on the implant osseointegration. The objective of this in vivo study is to determine the variation of the echographic ultrasonic response of a dental implant to bone healing around the implant interface. Twenty one dental implants were inserted in the femur of seven New Zealand white rabbits. Two animals were sacrificed after a healing duration of two weeks, three animals after six weeks and six animals after eleven weeks. The 10 MHz ultrasonic response of the implant was measured just after the implantation using a dedicated device positioned at the emerging surface of each dental implant. The measurements were realized again before the sacrifice with the same device. An indicator I˜ was derived based on the amplitude of the rf signal obtained for each configuration. The bone-Implant Contact (BIC) ratio was determined by histological analyses. The average value of the relative variation of the indicator I˜ obtained after initial surgery and after the corresponding healing period varies between 7% and 40%. A Kruskal-Wallis test (p<0.01) revealed a significant decrease of the value of the indicator I˜ as function of healing time. The indicator I˜ was significantly correlated (R(2)=0.45) with the BIC ratio. The results show that the ultrasonic response of a dental implant varies significantly as a function of healing time, which paves the way for the development of a new quantitative ultrasound (QUS) method in oral implantology.