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Updated: Apr 23, 2026

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
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Unfolded protein response activation in cataracts

Beatriz E Torres-Bernal1, Luis Fernando Torres-Bernal1, Rafael R Gutiérrez-Campos1

  • 1From Inova Vision Quirurgica (B.E. Torres-Bernal, L.F. Torres-Bernal), the Departamento de Química (Gutiérrez-Campos) and the Departamento de Morfología (Ventura-Juárez), Centro de Ciencias Básicas, the Departamento de Optometría (Barba-Gallardo) and Departamento de Cirurgia (L.F. Torres-Bernal), Centro de Ciencias de la Salud, Universidad Autónoma de Aguascalientes, Aguascalientes, the Instituto Nacional de Ciencias Médicas y de Nutrición Salvador Zubirán (Kershenobich Stalnikowitz), Mexico City, and CODET (Chayet), Vision Institute, Tijuana, Baja California, Mexico.

Journal of Cataract and Refractive Surgery
|September 30, 2014
PubMed
Summary

The unfolded protein response (UPR) factors, glucose-regulated protein 78 (GRP78) and activating transcription factor 6 (ATF6), are present in human cataracts. Their increased expression in diabetic cataracts suggests UPR

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