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Related Concept Videos

Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

8
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
8
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

21
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
21
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

8
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
8
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

21
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
21
Stroke: Introduction and Types01:29

Stroke: Introduction and Types

16
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
16

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Related Experiment Video

Updated: Apr 23, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

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Hip fracture after first-ever stroke: a population-based study.

H-L Lin1,2, H-C Lin3,4, Y-F Tseng1

  • 1Department of Neurology, Sijhih Cathay General Hospital, New Taipei City, Taiwan.

Acta Neurologica Scandinavica
|September 30, 2014
PubMed
Summary
This summary is machine-generated.

Stroke survivors face a higher hip fracture risk, particularly in the first four years post-stroke. Osteoporosis management is crucial for stroke patients, especially older females, to mitigate this risk.

Keywords:
hip fracturenational health insurance research datasetosteoporosisstroke

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Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
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Area of Science:

  • Gerontology
  • Neurology
  • Orthopedics

Background:

  • Stroke survivors have an elevated risk of subsequent hip fractures.
  • Osteoporosis is a significant risk factor for fractures in the elderly population.

Purpose of the Study:

  • To estimate the risk of hip fracture following a first-ever stroke.
  • To identify risk factors associated with hip fracture in stroke patients.

Main Methods:

  • Retrospective cohort study utilizing a nationwide population-based dataset.
  • Involved 18,413 stroke survivors and 18,413 matched control subjects.
  • Analyzed stroke type, time to fracture, comorbidities, and medication use.

Main Results:

  • Stroke patients had a higher incidence of hip fracture (4.3%) compared to controls (2.7%).
  • The relative risk of hip fracture was elevated in the first four years post-stroke, gradually declining thereafter.
  • Ageing, female sex, and antidepressant use were significant risk factors for hip fracture.

Conclusions:

  • Osteoporosis plays a key role in hip fractures within four years after stroke.
  • Early and sustained intervention for bone loss is recommended for stroke management, particularly for older females.
  • The benefits of antidepressants in stroke patients should be balanced against their potential to increase hip fracture risk.