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Updated: Apr 23, 2026

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
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Posttranslational modifications of RUNX1 as potential anticancer targets

S Goyama1, G Huang1, M Kurokawa2

  • 1Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Oncogene
|September 30, 2014
PubMed
Summary

RUNX1 is crucial in blood cell formation and cancer. Targeting its post-translational modifications (PTMs) offers a promising strategy for developing novel anticancer therapies.

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