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Related Experiment Video

Updated: Apr 23, 2026

Serial Two-Photon Tomography of the Whole Marmoset Brain for Neuroanatomical Analyses
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Brain-mapping projects using the common marmoset.

Hideyuki Okano1, Partha Mitra2

  • 1Laboratory for Marmoset Neural Architecture, Brain Science Institute RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan; Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.

Neuroscience Research
|September 30, 2014
PubMed
Summary

Global brain mapping initiatives, like Japan's Brain/MINDS project, are advancing neuroscience. This review details marmoset brain mapping strategies, highlighting its utility in understanding brain structure and function.

Keywords:
Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS)Brain-wide connectivity mapsDiffusion tensor imaging (DTI)Macroscopic structural mappingMesoscopic structural mappingMicroscopic structural mapping

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Area of Science:

  • Neuroscience
  • Comparative Anatomy

Background:

  • Global interest in brain mapping projects is rising, including initiatives in the USA, Europe, and Japan.
  • These projects aim to elucidate neuronal circuits for a comprehensive understanding of brain complexity.

Purpose of the Study:

  • To review strategies for structural and functional mapping of the common marmoset brain.
  • To discuss the relevance of the common marmoset as an animal model in neuroscience research.

Main Methods:

  • Focus on structural and functional mapping techniques applicable to the marmoset brain.
  • Comparative analysis of the common marmoset with other animal models.

Main Results:

  • The common marmoset (Callithrix jacchus) is a key model for the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project.
  • Advantages of the marmoset model include a developed frontal cortex, compact brain size, and available transgenic technologies.

Conclusions:

  • The common marmoset offers significant advantages for detailed brain mapping.
  • Understanding marmoset brain circuitry contributes to broader goals of human brain research.