Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Power Profiles of an Extended Depth of Focus Contact Lens for Myopia Management.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same author

Outcomes in the treatment of inner ear decompression sickness with hyperbaric oxygen therapy, a systematic review.

Diving and hyperbaric medicine·2026
Same author

Neural responses to acute hypoxia and hyperoxia.

Neuroscience·2026
Same author

A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal-Epidermal Composites Using Non-Adherent Microwell Arrays.

Bioengineering (Basel, Switzerland)·2025
Same author

Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions.

CPT: pharmacometrics & systems pharmacology·2025
Same author

AlphaWear Platform: Translating Wearable Sensors Data Into Decision Aids Using Open-Source Techniques.

Military medicine·2025

Related Experiment Video

Updated: Apr 23, 2026

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
06:48

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Published on: October 28, 2020

2.5K

In vivo real-time 3-D intracardiac echo using PMUT arrays.

David E Dausch, Kristin H Gilchrist, James B Carlson

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
    |September 30, 2014
    PubMed
    Summary

    New piezoelectric micromachined ultrasound transducer (PMUT) arrays enable real-time 3-D intracardiac imaging. These novel arrays with through-silicon interconnects offer high-resolution visualization within the heart.

    More Related Videos

    In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
    08:13

    In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

    Published on: February 16, 2016

    21.6K
    Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells
    10:37

    Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells

    Published on: March 14, 2021

    6.4K

    Related Experiment Videos

    Last Updated: Apr 23, 2026

    Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
    06:48

    Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

    Published on: October 28, 2020

    2.5K
    In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
    08:13

    In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

    Published on: February 16, 2016

    21.6K
    Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells
    10:37

    Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells

    Published on: March 14, 2021

    6.4K

    Area of Science:

    • Biomedical Engineering
    • Materials Science
    • Medical Imaging

    Background:

    • Intracardiac imaging requires high-resolution, real-time visualization for accurate diagnosis and intervention.
    • Traditional ultrasound probes face limitations in maneuverability and imaging depth within the heart.
    • Piezoelectric micromachined ultrasound transducers (PMUTs) offer miniaturization potential for advanced medical devices.

    Purpose of the Study:

    • To develop and evaluate novel PMUT matrix arrays with integrated through-silicon interconnects for intracardiac imaging.
    • To assess the feasibility of using these PMUT arrays for real-time, in vivo 3-D ultrasound imaging of cardiac structures.

    Main Methods:

    • Fabrication of 5 MHz PMUT arrays (256 and 512 elements) using bulk micromachining in silicon-on-insulator substrates.
    • Integration of novel through-silicon interconnects for individual addressing of PMUT elements.
    • Assembly of PMUT arrays into side-viewing 14-Fr catheters and testing in an adult porcine model via femoral vein access.

    Main Results:

    • Successful fabrication and operation of PMUT arrays with rectangular apertures at 5 MHz.
    • Demonstrated real-time 3-D imaging of the right atrium in a porcine model.
    • Achieved full 60° × 60° volume sectors with 8-10 cm penetration depth at 26-31 volumes/second.

    Conclusions:

    • The developed PMUT matrix arrays with through-silicon interconnects are suitable for intracardiac catheter integration.
    • This technology enables high-quality, real-time 3-D ultrasound imaging within the heart.
    • The findings suggest a promising advancement for minimally invasive cardiac diagnostics and interventions.