Coping with esophageal cancer approaches worldwide

Richard G H Cotton1, Rupert Langer, Trevor Leong

  • 1Human Variome Project International Limited, Department of Pathology, Florey Neuroscience Institutes, The University of Melbourne, Melbourne, Australia.

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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
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