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Capsule endoscopy followed by single balloon enteroscopy in children with obscure gastrointestinal bleeding: a

Salvatore Oliva1, Marco Pennazio2, Stanley A Cohen3

  • 1Department of Pediatrics, Paediatric Gastroenterology Unit, Sapienza - University of Rome, Rome, Italy.

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
|October 1, 2014
PubMed

Insights

This study shows a new diagnostic algorithm using capsule endoscopy, colon capsule endoscopy, and single-balloon enteroscopy is highly effective for diagnosing obscure gastrointestinal bleeding in children, achieving a 95% diagnostic yield.

Area of Science:

  • Pediatric Gastroenterology
  • Diagnostic Endoscopy
  • Gastrointestinal Bleeding

Background:

  • Obscure gastrointestinal bleeding (OGIB) in children presents diagnostic challenges.
  • Current diagnostic methods may have limitations in identifying the source of bleeding.

Purpose of the Study:

  • To evaluate a novel diagnostic algorithm for pediatric OGIB.
  • To assess the combined utility of capsule endoscopy, colon capsule endoscopy, and single-balloon enteroscopy.

Main Methods:

  • Prospective single-center study involving 22 pediatric patients with OGIB.
  • Sequential use of capsule endoscopy, colon capsule endoscopy, and single-balloon enteroscopy.
  • Comparison of findings and assessment of clinical outcomes.

Main Results:

  • The combined algorithm achieved a 95% diagnostic yield.
  • Capsule endoscopy identified positive findings in 63.6% of cases.
  • Therapeutic resolution was achieved in 82% of patients.

Conclusions:

  • The evaluated diagnostic algorithm demonstrates high efficacy for pediatric OGIB.
  • This approach offers significant diagnostic and therapeutic benefits.
  • Further multicenter studies are warranted to validate these findings.
Abstract

Keywords:
Capsule endoscopyChildrenEnteroscopyObscure gastrointestinal bleeding

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