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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
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Pediatric ischemic stroke due to dengue vasculitis
Subrat Kumar Nanda1, Sita Jayalakshmi1, Surath Mohandas1
1Department of Neurology, Krishna Institute of Medical Sciences, Secunderabad, Andhra Pradesh, India.
Pediatric Neurology
|October 1, 2014
Summary
Dengue infection can cause rare neurological complications like ischemic stroke in children, potentially due to immune-mediated vasculitis. Early consideration of dengue is crucial for childhood stroke diagnosis in endemic areas.
Area of Science:
- Neurology
- Pediatrics
- Infectious Diseases
Background:
- Dengue virus infection is a significant arboviral disease prevalent in Southeast Asia, particularly India.
- Neurological complications associated with dengue are increasingly being documented.
Observation:
- An 8-year-old girl presented with a febrile illness, headache, hemiparesis, and visual impairment.
- Brain MRI revealed multiple infarcts, and MRA showed vasculitis affecting cerebral and vertebral arteries.
- Dengue serology was positive for IgM antibodies.
Findings:
- The patient experienced an ischemic stroke attributed to dengue vasculitis.
- Cerebral artery narrowing indicated vasculitis, a rare dengue complication in a child.
- Treatment with corticosteroids led to complete recovery and resolution of vasculitis.
Implications:
- This case highlights immune-mediated vasculitis as a rare but possible cause of dengue-related stroke in children.
- Pediatric stroke evaluation in dengue-endemic regions should include consideration of dengue infection.
- Prompt diagnosis and management of dengue vasculitis can lead to favorable outcomes.
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