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Author Spotlight: Exploring Cloning Techniques for Full-Length DNA Fragments
Published on: May 17, 2024
Recombination in truncated genome sequences of porcine circovirus type 2
Libin Wen1, Fengzhi Wang, Kongwang He
1Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014, China, wlbwh@hotmail.com.
Abstract:
Porcine circovirus type 2 (PCV2) is the causal agent of a serious disease found in pigs. Here, we report the first detection of truncated genome sequences of PCV2 strain ZJ-R, with the genomic region encoding part of Rep and Cap with a nonviral insertion. To our knowledge, the genome of ZJ-R represents the first PCV2 DNA with a coding insertion. The PCV2 ZJ-R genome is 694 nucleotides long and has two main open reading frames. The whole genome sequence of ZJ-R may facilitate further study of the origin and evolution of PCV2.
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