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[Managing of platelet transfusion refractoriness of haematological malignancies. Experience IPC-EFSAM]

I Dettori1, P Ladaique2

  • 1Établissement français du sang Alpes-Méditerranée (EFSAM), 149, boulevard Baille, 13992 Marseille cedex 05, France.

The platelet refractoriness is a complication of transfusion treatments potentially dramatic in onco-haematology. Chemo-treatment of haematological malignancies or packs of allogeneic bone marrow transplants require iterative platelet transfusion requirements. The discovery of a platelet refractoriness along with its support should be the most reactive as possible but also adapted to the cause. In the case of allo-immunization, it may be expected. The purpose of this presentation is to recall the different etiologies and perform a feedback on the support transfusion platelet of onco-haematology adult patients at Institut Paoli-Calmettes (IPC) in partnership with the EFSAM.

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