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Updated: Apr 23, 2026

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation
Published on: January 20, 2018
Two birds with one stone: dendrimer surface engineering enables tunable periphery hydrophobicity and rapid endosomal
Zheng Wang1, Chao Chen, Ruihong Liu
1Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, School of Pharmaceutical Science & Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China. zhaoyj@tju.edu.cn.
Abstract:
Multifunctional thermosensitive dendrimeric nanocarriers were generated via tailored surface modification. Such design not only facilitated the rapid endosomal escape of dendrimers, but also achieved tunable surface hydrophobicity, which could be employed to achieve on-demand cargo release. These smart dendrimers are promising for enhancing intracellular drug delivery.

