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[Arrhythmia in patients with chronic heart insufficiency and type 2 diabetes mellitus]

V G Lychev, E B Klester, L A Plinokosova

    Klinicheskaia Meditsina
    |October 2, 2014
    PubMed

    Insights

    Patients with chronic heart insufficiency (CHI) and type 2 diabetes mellitus (DM2) experience frequent, prognostically unfavorable arrhythmias. These are linked to more severe myocardial dysfunction and diabetes-related complications.

    Area of Science:

    • Cardiology
    • Endocrinology
    • Clinical Research

    Context:

    • Arrhythmia is a common complication in patients with chronic heart insufficiency (CHI).
    • Type 2 diabetes mellitus (DM2) is a significant comorbidity that can exacerbate cardiovascular conditions.
    • Understanding the interplay between CHI, DM2, and arrhythmia is crucial for patient management.

    Purpose:

    • To investigate the characteristics, frequency, and peculiarities of arrhythmias in patients with CHI.
    • To analyze how the etiology of CHI and the presence of DM2 influence arrhythmia patterns.
    • To identify specific arrhythmia types prevalent in patients with combined CHI and DM2.

    Summary:

    • A study involving 197 patients with CHI and/or DM2 utilized clinical observation, EchoCG, 6-minute walk tests, and Holter ECG monitoring.
    • Results indicated high rates of ventricular arrhythmia (43.2%) and combined arrhythmias (41.2%) in patients with CHI and DM2.
    • Supraventricular arrhythmias were prevalent in 62.8% of DM2 patients, with combined arrhythmias being most frequent in the CHI+DM2 group.

    Impact:

    • Identifies specific arrhythmia profiles in patients with CHI and DM2, highlighting the increased risk in this population.
    • Emphasizes the role of myocardial failure severity and DM2-related factors (dysglycemia, neuropathy, nephropathy) in driving adverse arrhythmias.
    • Provides insights for targeted therapeutic strategies and improved prognostic assessment in patients with comorbid CHI and DM2.
    Abstract

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