Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Laser-enhanced angioplasty.

A T Garcia

    Texas Medicine
    |July 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    A novel balloon-guided laser system effectively ablated arteriosclerotic plaque in seven patients, enabling standard angioplasty for severe peripheral artery obstruction. This innovative approach shows promise in treating plaque buildup and potentially reducing restenosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    First Measurement of the |t| Dependence of Incoherent J/ψ Photonuclear Production.

    Physical review letters·2024
    Same author

    Expression and genetic variation of the Aplysia egg-laying hormone gene family in the atrial gland.

    Invertebrate neuroscience : IN·1997
    Same author

    Molecular cloning and cellular localization of a furin-like prohormone convertase from the atrial gland of Aplysia.

    DNA and cell biology·1995
    Same author

    Molecular cloning, cDNA sequence, and localization of a prohormone convertase (PC2) from the Aplysia atrial gland.

    DNA and cell biology·1995
    Same author

    Extended treatment with diltiazem hydrochloride successful.

    Texas medicine·1993
    Same author

    Occurrence of a furin-like prohormone processing enzyme in Aplysia neuroendocrine bag cells.

    Comparative biochemistry and physiology. B, Comparative biochemistry·1993
    Same journal

    Commentary: This Is Not a Drill.

    Texas medicine·2021
    Same journal

    Healthy Determination: Texas Physicians are Finding Better Ways to Address Their Patients' Social Determinants of Health.

    Texas medicine·2021
    Same journal

    Going Local: Accountable Health Organizations Could Help Combat Social Disparities at the Local Level.

    Texas medicine·2021
    Same journal

    Data Driven: Medicaid's Inspector General Focuses on Fraud Prevention, Not Just Prosecution.

    Texas medicine·2021
    Same journal

    Talk to Patients About: Vaccine Adverse Event Reporting System (VAERS).

    Texas medicine·2021
    Same journal

    Obstacles to Clear.

    Texas medicine·2021
    See all related articles

    Area of Science:

    • Cardiovascular Medicine
    • Medical Devices
    • Interventional Cardiology

    Background:

    • Peripheral artery obstruction is a significant cause of morbidity.
    • Standard angioplasty can be limited by plaque burden and risk of complications.
    • Arteriosclerotic plaque removal is crucial for effective revascularization.

    Observation:

    • A balloon-guided laser system (Lastac System) was utilized to ablate arteriosclerotic plaque.
    • The system employs a balloon to center the laser, minimizing vessel perforation risk.
    • Integrated features include a control monitor, a narrowed laser beam, and a cooling/clearing infusion pump.

    Findings:

    • Successful plaque ablation was achieved in seven patients with severe peripheral artery obstruction.
    • All treated patients remained free of claudication post-procedure.

    Related Experiment Videos

  • One patient experienced a clinically insignificant vessel perforation.
  • Implications:

    • The Lastac System demonstrates effectiveness in plaque elimination for peripheral artery disease.
    • This technology may offer a safer alternative to traditional angioplasty for complex lesions.
    • Further studies with larger patient cohorts are warranted to confirm efficacy and impact on restenosis rates.