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Related Concept Videos

An Overview of the Endocrine System01:10

An Overview of the Endocrine System

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The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
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Structures of the Endocrine System00:59

Structures of the Endocrine System

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The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
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The Endocrine System01:29

The Endocrine System

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The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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What is the Endocrine System?00:46

What is the Endocrine System?

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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

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Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features...
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Cushing Syndrome I: Introduction01:26

Cushing Syndrome I: Introduction

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Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the...
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Phaeochromocytoma in multiple endocrine neoplasia type 2: RET codon-specific penetrance and changes in management during the last four decades.

Clinical endocrinology·2017
Same author

Long-Term Follow-Up and Treatment of Postoperative Permanent Hypoparathyroidism in Patients with Medullary Thyroid Carcinoma: Differences in Complete and Partial Disease.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2016
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[Endocrine tumors and their therapy].

Der Radiologe·2014
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[Secondary osteoporosis - relevant clinical characteristics in diagnosis and therapy].

Deutsche medizinische Wochenschrift (1946)·2012
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[Hereditary variants of primary hyperparathyroidism--MEN1, MEN2, HPT-JT, FHH, FIHPT].

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Are commonly recommended dosages for vitamin D supplementation too low? Vitamin D status and effects of supplementation on serum 25-hydroxyvitamin D levels--an observational study during clinical practice conditions.

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Related Experiment Video

Updated: Apr 23, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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[Endocrine tumors: clinical overview].

G Leidig-Bruckner1

  • 1Gemeinschaftspraxis Endokrinologie & Nuklearmedizin, Brückenstr. 21, 69120, Heidelberg, Deutschland, gudrun.leidigbruckner@raue-praxis.de.

Der Radiologe
|October 2, 2014
PubMed
Summary

This article overviews endocrine tumors, covering their classification, diagnosis, and treatment. Early detection and genetic screening are crucial for hereditary endocrine tumors, improving patient outcomes.

Area of Science:

  • Endocrinology
  • Oncology
  • Genetics

Context:

  • Endocrine tumors arise from various endocrine organs, presenting diverse characteristics like localization, function, and hereditary patterns.
  • Clinical presentation, symptoms, and physical examination are key for diagnosing functioning endocrine tumors.
  • Advancements in imaging techniques lead to increased incidentaloma detection in endocrine glands.

Purpose:

  • To provide an overview of endocrine tumors, including their unique features.
  • To summarize clinical and diagnostic approaches for endocrine tumors.
  • To highlight the importance of early diagnosis and treatment, especially in hereditary syndromes.

Summary:

  • Endocrine tumors are classified by location, function, and hereditary status, influencing clinical outcomes.

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  • Diagnosis involves clinical history, laboratory endocrine parameters, and imaging, with genetic testing vital for hereditary forms.
  • Management strategies for incidentalomas focus on functional status and malignancy risk.

    • Impact:

    • Facilitates a better understanding of endocrine tumor diagnosis and management.
    • Emphasizes the benefits of early detection and intervention in hereditary endocrine tumor syndromes.
    • Provides a foundation for optimizing therapeutic decisions in endocrine oncology.