Related Experiment Video
Updated: Apr 23, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
Published on: April 19, 2021
A firmware-defined digital direct-sampling NMR spectrometer for condensed matter physics
M Pikulski1, T Shiroka1, H-R Ott1
1Laboratorium für Festkörperphysik, ETH Hönggerberg, CH-8093 Zürich, Switzerland and Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland.
A new digital, broad-band nuclear magnetic resonance (NMR) spectrometer was developed for condensed matter research. This flexible, software-defined instrument offers competitive performance and easy replication for advanced studies.
Area of Science:
- Condensed Matter Physics
- Spectroscopy
- Digital Instrumentation
Background:
- Traditional Nuclear Magnetic Resonance (NMR) spectrometers can be complex and expensive.
- There is a need for flexible, adaptable, and cost-effective instrumentation for condensed matter research.
Purpose of the Study:
- To design and implement a novel digital, broad-band NMR spectrometer.
- To create a versatile and extensible platform for condensed matter probing.
- To demonstrate competitive performance compared to conventional NMR systems.
Main Methods:
- Utilized direct sampling in transmission and reception.
- Employed a single, commercially available signal processing device with a Field-Programmable Gate Array (FPGA).
- Defined spectrometer functions via FPGA firmware and application software.
Main Results:
- The digital NMR spectrometer operates up to 400 MHz (800 MHz with undersampling).
- Features digital down-conversion with a ±10 MHz passband and supports high repetition rates.
- Demonstrated competitive performance through test data, comparable to conventional designs.
Conclusions:
- The developed software-based NMR spectrometer offers flexibility, fast replication, and extensibility.
- Components can be reused for other projects, enhancing value.
- The system provides a viable, high-performance alternative for condensed matter research.
Related Concept Videos
NMR Spectrometers: Overview
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
NMR Spectrometers: Resolution and Error Correction
NMR Spectroscopy: Chemical Shift Overview
For instance, the proton...
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
Raman Spectroscopy Instrumentation: Overview
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...

