Related Experiment Video
Updated: Apr 23, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Ventriculo-atrial defect after bioprosthetic aortic valve replacement
Jayant S Jainandunsing1, Remco Bergman2, Jacob Wilkens3
1Department of Anesthesia and Pain Medicine, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, 9700 RB, The Netherlands. j.s.jainandunsing@umcg.nl.
This case report details a rare ventriculo-atrial defect, a type of Gerbode defect, caused by infective endocarditis near a prosthetic aortic valve. It highlights a novel cause of this uncommon cardiac defect.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Pathology
Background:
- Ventriculo-atrial defects are rare cardiac abnormalities.
- Infective endocarditis can lead to abscess formation and subsequent defects.
- Gerbode defects, specifically, are uncommon and typically involve native cardiac tissue.
Observation:
- A 71-year-old male presented with a ventriculo-atrial defect.
- The defect originated from the aortic root adjacent to a bioprosthetic aortic valve implanted 4 years prior.
- Infective endocarditis was identified as the cause, leading to inflammation and a paravalvular prosthetic defect.
Findings:
- This case represents a novel third type of Gerbode defect, specifically a ventriculo-atrial defect secondary to inflammation of a paravalvular aortic prosthetic defect.
- The defect resulted from infective endocarditis affecting the aortic root and prosthetic valve.
Implications:
- This report expands the known etiologies of Gerbode defects to include paravalvular prosthetic complications.
- Understanding this rare presentation is crucial for accurate diagnosis and surgical management of similar cases.
- Highlights the importance of considering prosthetic valve complications in infective endocarditis.
Related Concept Videos
Aortic Regurgitation I: Introduction
Aneurysm III: Interprofessional Care
Aortic Regurgitation III: Medical Management
Aortic Regurgitation II: Clinical Features and Diagnostic Tests

