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Updated: Apr 23, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Short-term outcome of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: preliminary analysis of a
Antonio Macrì1, Vincenzo Arcoraci2, Valerio Belgrano3
1Department of Human Pathology, University of Messina, Messina, Italy amacri@unime.it.
Aim:
To assess the incidence of morbidity and mortality of Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy.
Patients And Methods:
A retrospective multicentric study was performed. Six hundred and eighty-three patients were recorded. Predictors of morbidity and mortality were evaluated with univariate and multivariate analysis.
Results:
In univariate analysis, older age, Eastern Cooperative Oncology Group score, a greater value of Peritoneal Cancer Index (PCI) and sub-optimal cytoreduction were correlated with higher mortality, while older age, presence of ascites, ovarian origin of carcinomatosis, closed technique, a greater value of PCI, longer operative time and sub-optimal cytoreduction were predictors of higher morbidity. In multivariate analysis, older age and a greater value of PCI were correlated with higher mortality; older age, ovarian origin of tumor, presence of ascites, closed technique and longer operative time were predictors of higher morbidity.
Conclusion:
Careful patient selection has to be performed to improve clinical outcomes.
