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Endovascular recanalization for chronic symptomatic intracranial vertebral artery total occlusion

Ziqi Xu1, Ning Ma2, Dapeng Mo2

  • 1Department of Neurology, The First Affiliated Hospital of College of Medicine, Zhejiang University, No. 79 QingChun Road, Hangzhou, Zhejiang 310003, China.

Minimally Invasive Surgery
|October 3, 2014
PubMed

Insights

Stenting for chronic symptomatic intracranial vertebral artery total occlusion is feasible. This endovascular therapy improved patient outcomes, offering a potential treatment option for selected individuals.

Area of Science:

  • Neurology
  • Interventional Neuroradiology
  • Vascular Surgery

Background:

  • Chronic symptomatic intracranial vertebral artery (ICVA) total occlusion presents poor recanalization outcomes.
  • Limited treatment options exist for patients with ICVA total occlusion, impacting neurological function.

Purpose of the Study:

  • To evaluate the technical feasibility and long-term outcomes of stenting for ICVA total occlusion.
  • To assess the safety and efficacy of endovascular recanalization in this patient cohort.

Main Methods:

  • Retrospective review of a prospectively maintained intracranial intervention database.
  • Identification of patients with symptomatic ICVA total occlusion treated more than one month after the index ischemic event.
  • Analysis of endovascular recanalization procedures and periprocedural complications.

Main Results:

  • Eight patients (mean age 58) with symptomatic ICVA total occlusion were identified.
  • Endovascular recanalization was attempted in seven patients, achieving successful revascularization in six.
  • Clinical improvement was observed in most patients post-intervention, despite periprocedural complications in three.

Conclusions:

  • Stent-supported recanalization of ICVA total occlusion is technically feasible.
  • Endovascular therapy may represent a viable treatment option for carefully selected patients with ICVA total occlusion.
  • Further research is warranted to optimize outcomes and minimize risks in this challenging condition.

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