Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neurotransmitters01:31

Neurotransmitters

3.7K
Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.
3.7K
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

5.0K
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
5.0K
Hormonal Regulation01:33

Hormonal Regulation

30.1K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
30.1K
Hormonal Regulation01:40

Hormonal Regulation

37.4K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
37.4K
Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

13.4K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
13.4K
Thermal Stress01:09

Thermal Stress

2.5K
If the temperature of an object is changed while it is prevented from expanding or contracting, the object is subjected to stress. The stress is compressive if the object expands in the absence of constraint and tensile if it contracts. This stress resulting from temperature change is known as thermal stress. It can be quite large and can cause damage. To avoid this stress, engineers may design components so they can expand and contract freely. For instance, on highways, gaps are deliberately...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Navigating Change, Sustaining Impact: GHSP's Mission in a Transformed Landscape.

Global health, science and practice·2026
Same author

"Community Over Commercialization": Help Us Keep GHSP Open.

Global health, science and practice·2025
Same author

Comparing apples with apples: A proposed taxonomy for "Community Health Workers" and other front-line health workers for international comparisons.

PLOS global public health·2025
Same author

Strengthening primary health care through community health workers in South Asia.

The Lancet regional health. Southeast Asia·2024
Same author

Linking weather and health outcomes: Examining the potential influences of weather factors and particulate matter pollution on adverse pregnancy outcomes in the Kavre district, Nepal.

Environmental research·2024
Same author

Masking for COVID-19 and other respiratory viral infections: implications of the available evidence.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2024

Related Experiment Video

Updated: Apr 23, 2026

Measuring Skeletal Muscle Thermogenesis in Mice and Rats
07:56

Measuring Skeletal Muscle Thermogenesis in Mice and Rats

Published on: July 27, 2022

2.7K

Oxytocin: taking the heat.

Stephen Hodgins1

  • 1Global Health: Science and Practice, Associate Editor for Maternal and Child Health.

Global Health, Science and Practice
|October 3, 2014
PubMed
Summary
This summary is machine-generated.

Oxytocin-in-Uniject met temperature standards for storage but requires frequent resupply. Future improvements may involve integrating temperature-time indicators with conventional oxytocin vials or exploring lower, effective doses.

More Related Videos

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding
09:12

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Published on: November 14, 2018

7.1K
Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
07:56

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development

Published on: January 26, 2018

20.0K

Related Experiment Videos

Last Updated: Apr 23, 2026

Measuring Skeletal Muscle Thermogenesis in Mice and Rats
07:56

Measuring Skeletal Muscle Thermogenesis in Mice and Rats

Published on: July 27, 2022

2.7K
Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding
09:12

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Published on: November 14, 2018

7.1K
Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
07:56

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development

Published on: January 26, 2018

20.0K

Area of Science:

  • Obstetrics and Gynecology
  • Pharmaceutical Science
  • Public Health

Background:

  • Postpartum hemorrhage (PPH) remains a leading cause of maternal mortality globally.
  • Oxytocin is a critical uterotonic agent for PPH prevention.
  • Ensuring oxytocin stability under diverse storage conditions is vital for effective PPH management.

Purpose of the Study:

  • To evaluate the performance of Oxytocin-in-Uniject under severe home storage conditions.
  • To identify logistical challenges associated with the current Oxytocin-in-Uniject supply chain.
  • To propose potential advancements for improving oxytocin delivery and stability.

Main Methods:

  • Assessment of Oxytocin-in-Uniject against temperature-time indicator (TTI) standards.
  • Analysis of resupply frequency and logistical implications.
  • Exploration of alternative strategies for oxytocin temperature monitoring and formulation.

Main Results:

  • Oxytocin-in-Uniject met TTI standards even in harsh storage environments.
  • The 30-day resupply requirement presents significant logistical challenges.
  • Several potential improvements were identified for future oxytocin delivery systems.

Conclusions:

  • While Oxytocin-in-Uniject demonstrates temperature stability, its logistical demands require optimization.
  • Integrating TTIs with conventional oxytocin vials could offer a more sustainable solution.
  • Further research into optimized dosing and calibration of TTIs is warranted to enhance PPH prevention strategies.