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[Seborrheic keratoses studied using scanning electron microscopy].

P L Bencini, A Pincelli, M Carducci

    Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia
    |January 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    Scanning electron microscopy revealed two distinct processes in acanthotic seborrheic keratosis development. These involve keratinocyte groups forming horny cysts via extrafollicular and follicular pathways.

    Area of Science:

    • Dermatopathology
    • Electron Microscopy

    Context:

    • Seborrheic keratosis is a common benign epidermal tumor.
    • The acanthotic type exhibits unique morphological features.

    Purpose:

    • To investigate the ultrastructural morphology of acanthotic seborrheic keratosis using scanning electron microscopy (SEM).
    • To elucidate the distinct processes involved in the formation of horny cysts.

    Summary:

    • SEM analysis of ten acanthotic seborrheic keratosis cases identified two primary pathways for horny cyst genesis.
    • An extrafollicular process involves keratinocyte groups forming vortex patterns and concentric keratinization.
    • A follicular process leads to accentuated keratinization around the epithelial sheath, often with multiple hairs per follicle.

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    Impact:

    • Provides detailed ultrastructural insights into seborrheic keratosis pathogenesis.
    • Highlights the role of specific keratinization processes in lesion development.
    • Observes microbial presence and membrane alterations, suggesting potential contributing factors.