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09:03
Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus
Published on: September 5, 2013
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Genome Assembly of Methicillin-Resistant Quality Control Strain Staphylococcus aureus CDC73-57501 (ATCC 29247)
H E Daligault1, K W Davenport1, T D Minogue2
1Los Alamos National Laboratory (LANL), Los Alamos, New Mexico, USA.
Genome Announcements
|October 4, 2014
Summary
We present the genome assembly for Staphylococcus aureus CDC73-57501, a methicillin-resistant strain. This assembly aids in understanding antibiotic resistance in this common bacterial pathogen.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Staphylococcus aureus is a significant cause of bacterial infections in the US.
- High rates of resistance to beta-lactam antibiotics are observed in S. aureus infections.
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a substantial public health threat.
Purpose of the Study:
- To provide a high-quality, scaffolded genome assembly for S. aureus CDC73-57501 (ATCC 29247).
- To establish a genomic resource for a well-characterized methicillin-resistant quality control strain.
Main Methods:
- Whole-genome sequencing of S. aureus CDC73-57501.
- Bioinformatic analysis for scaffolded genome assembly.
- Assembly into 16 contigs.
Main Results:
- Successful scaffolded genome assembly of S. aureus CDC73-57501 into 16 contigs.
- The assembly provides a detailed genomic blueprint of this MRSA strain.
Conclusions:
- The genome assembly of S. aureus CDC73-57501 offers a valuable resource for research.
- Facilitates further studies into antibiotic resistance mechanisms and development of control strategies.
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