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Racial and ethnic differences in the risk of postpartum venous thromboembolism: a population-based, case-control
M Blondon1, L B Harrington, M Righini
1Division of Angiology and Haemostasis, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland; Department of Epidemiology, University of Washington, Seattle, WA, USA.
Journal of Thrombosis and Haemostasis : JTH
|October 4, 2014
Summary
Maternal race/ethnicity impacts postpartum venous thromboembolism (VTE) risk. Black women face higher VTE risk, while Asian women have lower risk compared to white women.
Area of Science:
- Obstetrics and Gynecology
- Maternal Health
- Thrombosis Research
Background:
- Venous thromboembolism (VTE) is a significant cause of maternal morbidity and mortality.
- The association between maternal race/ethnicity and postpartum VTE risk is not well-established.
Purpose of the Study:
- To investigate the relationship between maternal race/ethnicity and the risk of postpartum VTE.
- To determine if race/ethnicity is an independent risk factor for postpartum VTE.
Main Methods:
- Population-based case-control study in Washington State (1987-2011).
- Identified 688 postpartum VTE cases and 10,246 controls.
- Used logistic regression to compare VTE risk across racial/ethnic groups, adjusting for covariates.
Main Results:
- Black women had a significantly higher risk of postpartum VTE (aOR 1.50) compared to non-Hispanic white women.
- Asian women had a significantly lower risk (aOR 0.67).
- Hispanic women showed a trend towards lower risk (aOR 0.80), but it was not statistically significant. Increased risk for Black women was noted with cesarean delivery.
Conclusions:
- Maternal race/ethnicity is independently associated with postpartum VTE risk.
- Consideration of race/ethnicity is important for assessing thromboprophylaxis needs post-delivery.
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