Ovarian wedge resection with contact Nd:YAG laser irradiation used laparoscopically

Twelve women with polycystic ovary disease were treated with Nd:YAG laser contact irradiation using a cutting-type probe. Bilateral ovarian wedge resection was performed in every case. After undergoing the procedure, seven patients achieved pregnancy, and another three experienced the return of a normal menstrual cycle. Serum testosterone and androstenedione levels were decreased postoperatively, while luteinizing hormone (LH), follicle stimulating hormone (FSH) and estradiol were increased. It seems that the decrease in intraovarian androgens might have reduced the negative feedback system and thus might have increased the secretion of gonadotropin and estradiol, which in turn promoted ovulation induction and pregnancy.