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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

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Prevalence and risk factors of abnormal left ventricular geometrical patterns in untreated hypertensive patients

Hui Li, Fei Pei, Liying Shao

  • 1Department of Cardiology, The First Hospital Affiliated to Shanxi Medical University, 85 Jiefang South Road, Taiyuan City, Shanxi Province 030001, China. ganxibaozhongxin@sina.com.

BMC Cardiovascular Disorders
|October 5, 2014
PubMed

Insights

Left ventricular hypertrophy (LVH) and abnormal geometry are more common in older women with untreated hypertension. Key risk factors include age, female sex, high blood pressure, and body mass index, highlighting the need for hypertension awareness.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Echocardiography

Background:

  • Left ventricular hypertrophy (LVH) and abnormal left ventricular (LV) geometry exhibit varied prevalence across populations.
  • Limited data exists on LV geometric patterns in a large cohort of Chinese individuals with untreated hypertension.

Purpose of the Study:

  • To investigate the prevalence of LVH and abnormal LV geometric patterns in a substantial group of untreated hypertensive Chinese patients.
  • To identify the demographic and clinical risk factors associated with LVH and abnormal LV geometry in this population.

Main Methods:

  • A cross-sectional study involving 1641 untreated hypertensive patients (1044 males, 597 females).
  • LV geometry was categorized into normal, concentric remodeling, concentric hypertrophy, and eccentric hypertrophy using LV mass index (LVMI) and relative wall thickness (RWT).
  • Logistic regression analysis was employed to determine risk factors for LVH and abnormal LV geometry.

Main Results:

  • The overall prevalence of LVH was 20.2%, significantly higher in women (30.8%) than men (14.2%).
  • Prevalence rates for abnormal LV geometry included concentric remodeling (34.9%), concentric hypertrophy (11.1%), and eccentric hypertrophy (9.1%).
  • Adjusted analysis identified age, female sex, systolic blood pressure, and body mass index as significant risk factors for LVH and abnormal geometry; low HDL may also be a contributing factor.

Conclusions:

  • LVH and abnormal LV geometric patterns are more prevalent in women and increase with age among untreated hypertensive individuals.
  • Improving hypertension awareness and managing cardiovascular risk factors are critical in this patient group.
Abstract

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