Related Experiment Video
Updated: Apr 23, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Temperature variation between neighboring days and mortality: a distributed lag non-linear analysis.
Jian Cheng1, Rui Zhu, Zhiwei Xu
1Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui, China.
Sudden temperature changes between days significantly impact mortality. Daily temperature increases are linked to higher non-accidental and cardiovascular deaths, while decreases show a protective effect, especially in older males.
Area of Science:
- Environmental Health
- Epidemiology
- Climate Science
Background:
- Climate change necessitates understanding extreme weather impacts.
- Daily temperature fluctuations are a critical, understudied environmental stressor.
- Subtropical regions face unique challenges from temperature variability.
Purpose of the Study:
- To quantify the association between daily temperature changes and mortality.
- To investigate differential impacts across age and sex demographics.
- To inform public health interventions for climate-related risks.
Main Methods:
- Utilized Poisson generalized linear regression and distributed lag non-linear models.
- Analyzed daily mortality data from a subtropical Chinese city (2008-2012).
- Calculated temperature change as the difference between consecutive days' temperatures.
Main Results:
- Significant associations were found between daily temperature change and mortality.
- Temperature increases correlated with higher non-accidental and cardiovascular mortality.
- Temperature decreases showed a protective effect on non-accidental and cardiovascular mortality, particularly in males and individuals aged 65+.
Conclusions:
- Daily temperature variation poses a significant adverse health risk.
- Temperature increases between days are linked to increased mortality.
- Future climate change mitigation must consider daily temperature fluctuations.
Related Concept Videos
Derivatives: Problem Solving
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
Life Tables
Hazard Rate
Noncompartmental Analysis: Mean Residence Time
After the administration of a drug through intravenous bolus injection, the drug molecules are distributed throughout the body and remain there for varying periods. The MRT represents the average time these drug molecules stay in the...
Introduction To Survival Analysis
The primary goal of survival analysis is to estimate survival time—the time...

