Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

1.3K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.3K
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

2.1K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.1K
Parkinson Disease l: Introduction01:24

Parkinson Disease l: Introduction

6
Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of...
6
Parkinson Disease ll: Pathophysiology01:24

Parkinson Disease ll: Pathophysiology

13
Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...
13
Taste Buds and Receptors01:20

Taste Buds and Receptors

5.5K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
5.5K
Neural Regulation01:37

Neural Regulation

34.5K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
34.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reprogramming of updated neurostimulators in chronically implanted patients with Parkinson's disease: A double-blind randomized controlled trial.

Brain stimulation·2025
Same author

Parkinsonism and Bilateral Facial Palsy after Chimeric Antigen Receptor T-Cell Therapy.

Movement disorders clinical practice·2025
Same author

Deep Brain Stimulation in Pediatric Populations: A Scoping Review of the Clinical Trial Landscape.

Stereotactic and functional neurosurgery·2025
Same author

Challenges in Describing Tremor and Dystonia.

Neurology·2024
Same author

Closed-loop systems for deep brain stimulation to treat neuropsychiatric disorders.

Expert review of medical devices·2024
Same author

Deep Brain Stimulation of the Nucleus Accumbens for Severe Self-Injurious Behavior in Children: A Phase I Pilot Trial.

Biological psychiatry·2024

Related Experiment Video

Updated: Apr 23, 2026

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
05:51

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Published on: October 14, 2021

3.6K

Taste in Parkinson's disease.

Maria Paola Cecchini1, Alfonso Fasano, Federico Boschi

  • 1Department of Neurological and Movement Sciences, Anatomy and Histology Section, University of Verona, Strada le Grazie, 8, 37134, Verona, Italy, mariapaola.cecchini@univr.it.

Journal of Neurology
|October 5, 2014
PubMed
Summary

Parkinson's disease affects more than just motor skills, often impacting senses. This review explores taste dysfunction in Parkinson's disease, examining current research and evaluation methods.

More Related Videos

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease
10:32

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Published on: June 17, 2013

56.9K
Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease
03:20

Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease

Published on: September 22, 2023

2.7K

Related Experiment Videos

Last Updated: Apr 23, 2026

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
05:51

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Published on: October 14, 2021

3.6K
Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease
10:32

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Published on: June 17, 2013

56.9K
Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease
03:20

Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease

Published on: September 22, 2023

2.7K

Area of Science:

  • Neurology
  • Neuroscience
  • Chemosensory Science

Background:

  • Parkinson's disease (PD) is increasingly recognized as a systemic illness with diverse non-motor symptoms.
  • Chemosensory dysfunction, particularly olfactory impairment, is a well-established early symptom of PD.
  • The role and characteristics of taste dysfunction in PD remain less understood.

Purpose of the Study:

  • To review and synthesize the current literature on taste function in Parkinson's disease.
  • To clarify the incidence, scope, and underlying mechanisms of taste alterations in PD patients.
  • To discuss methodologies for taste assessment and identify areas for future research.

Main Methods:

  • Systematic literature search of studies investigating taste function in Parkinson's disease.
  • Analysis of reported taste alterations, including specific taste modalities affected.
  • Review of diagnostic tools and methodologies used for taste evaluation in PD research.

Main Results:

  • Evidence suggests taste dysfunction is prevalent in Parkinson's disease, though less studied than smell deficits.
  • Specific taste impairments (e.g., reduced sweet or salt perception) are reported, but findings vary across studies.
  • Pathophysiological links between PD and taste alterations are not fully elucidated.

Conclusions:

  • Taste dysfunction is a significant non-motor symptom in Parkinson's disease that warrants further investigation.
  • Standardized taste assessment methods are needed to improve the reliability and comparability of research findings.
  • Future research should focus on the pathophysiology and clinical implications of taste changes in PD.