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Updated: Apr 23, 2026
Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
Published on: March 21, 2018
Electrochemical sensor based on magnetic graphene oxide@gold nanoparticles-molecular imprinted polymers for
Xiangjun Li1, Xiaojiao Wang1, Leilei Li1
1Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong (University of Jinan), School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, PR China.
Abstract:
A novel composite of magnetic graphene oxide @ gold nanoparticles-molecular imprinted polymers (MGO@AuNPs-MIPs) was synthesized and applied as a molecular recognition element to construct dibutyl phthalate (DBP) electrochemical sensor. The composite of MGO@AuNPs was first synthesized using coprecipitation and self-assembly technique. Then the template molecules (DBP) were absorbed at the MGO@AuNPs surface due to their excellent affinity, and subsequently, selective copolymerization of methacrylic acid and ethylene glycol dimethacrylate was further achieved at the MGO@AuNPs surface. Potential scanning was presented to extract DBP molecules from the imprinted polymers film rapidly and completely. As a consequence, an electrochemical sensor for highly sensitive and selective detection of DBP was successfully constructed as demonstration based on the synthesized MGO@AuNPs-MIPs composite. Under optimal experimental conditions, selective detection of DBP in a linear concentration range of 2.5 × 10(-9)-5.0 × 10(-6)mol/L was obtained. The new DBP electrochemical sensor also exhibited excellent repeatability, which expressed as relative standard deviation (RSD) was about 2.50% for 30 repeated analyses of 2.0 × 10(-6)mol/L DBP.
