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Changes in tissue directionality reflect differences in myelin content after demyelination in mice spinal cords

Mohammad K Ansari1, Heather Y F Yong2, Luanne Metz1

  • 1Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta T2N 1N4, Canada.

Journal of Structural Biology
|October 5, 2014
PubMed
Summary

Structure tensor analysis quantifies myelin integrity in mouse spinal cords. Greater myelin content correlates with higher tissue anisotropy, offering a new tool for demyelinating disease research.

Keywords:
DemyelinationMultiple sclerosisMyelin contentSpinal cordStructure tensor analysisTissue directionality

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