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Updated: Apr 23, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Bulky mediastinal aspergillosis mimicking cancer in an immunocompetent patient
Jean-Baptiste Stern1, Benjamin Wyplosz2, Pierre Validire3
1Département Thoracique, Institut Mutualiste Montsouris, Paris, France; Assistance Publique-hôpitaux de Paris, CHU Bicêtre, Service des maladies infectieuses et tropicales, Le Kremlin-Bicêtre, France.
Abstract:
We describe the case of a previously healthy 42-year-old woman who presented with a chronic cough and occasional night sweats. Radiologic exploration showed a bulky mediastinal mass surrounding the aortic arch, associated with a left subclavicular lymph node and a cerebral round lesion, mimicking a disseminated lung cancer. Surgical left subclavicular and computed tomography-guided mediastinal biopsy specimens showed granulomatous patterns. Mycologic culture of both samples grew Aspergillus flavus. Resolution was obtained after 9 months of oral voriconazole therapy.
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