Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Teratogenicity01:07

Teratogenicity

4.2K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.2K
Improving Translational Accuracy02:07

Improving Translational Accuracy

2.6K
2.6K
Improving Translational Accuracy02:07

Improving Translational Accuracy

11.5K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
11.5K
LTR Retrotransposons03:08

LTR Retrotransposons

18.0K
LTR retrotransposons are class I transposable elements with long terminal repeats flanking an internal coding region. These elements are less abundant in mammals compared to other class I transposable elements. About 8 percent of human genomic DNA comprises LTR retrotransposons. Some of the common examples of LTR retrotransposons are Ty elements in yeast and Copia elements in Drosophila.
The internal coding region of LTR retrotransposons and their mechanism of transposition closely resembles a...
18.0K
Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

12.4K
As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
12.4K
Overview of Transposition and Recombination02:13

Overview of Transposition and Recombination

16.2K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
16.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role, impact, and feasibility of a comprehensive pharmacist medication review for patients in the older adult cancer clinic (OACC) at Princess Margaret Cancer Centre.

Journal of geriatric oncology·2026
Same author

Barriers and facilitators to sexual and reproductive health services among adolescents and young adults in Sidama region, Ethiopia: a qualitative study.

Reproductive health·2026
Same author

Exploring the preference of devices that can measure movement among people who have been hospitalised: A discrete choice experiment.

Digital health·2026
Same author

Implementation of co-designed strategies enhances referral to pulmonary rehabilitation for people with COPD in tertiary care: an interrupted time series study.

Implementation science : IS·2026
Same author

Dialling in for breastfeeding success, a mixed-methods approach to explore remote stakeholders' perceptions and experiences of the use of telehealth for lactation support.

Rural and remote health·2026
Same author

Lung cancer risk prediction models and asbestos exposure: a validation study on the Western Australia Asbestos Review Program.

Occupational and environmental medicine·2026
Same journal

Ensuring the health of hospital boilers.

Health estate·2018
Same journal

Solar PV - a bright future forecast.

Health estate·2018
Same journal

Removing the stigma, changing perceptions.

Health estate·2018
Same journal

Designing a tap to meet multiple criteria.

Health estate·2018
Same journal

Getting the sensory aspects right.

Health estate·2018
Same journal

Challenges set by the ErP Directive addressed.

Health estate·2018
See all related articles

Related Experiment Video

Updated: Apr 23, 2026

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs
11:21

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs

Published on: September 10, 2017

9.1K

TR/19 update--key concerns addressed.

Richard Norman

    Health Estate
    |October 7, 2014
    PubMed
    Summary
    This summary is machine-generated.

    The Building and Engineering Services Association (B&ES) updated its TR/19 guidance on ventilation system cleanliness. These revisions address crucial aspects of maintaining healthy indoor air quality in HVAC systems.

    More Related Videos

    Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
    09:34

    Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

    Published on: February 17, 2022

    2.9K
    Translating Ribosome Affinity Purification TRAP to Investigate Arabidopsis thaliana Root Development at a Cell Type-Specific Scale
    09:41

    Translating Ribosome Affinity Purification TRAP to Investigate Arabidopsis thaliana Root Development at a Cell Type-Specific Scale

    Published on: May 14, 2020

    11.7K

    Related Experiment Videos

    Last Updated: Apr 23, 2026

    Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs
    11:21

    Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs

    Published on: September 10, 2017

    9.1K
    Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
    09:34

    Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

    Published on: February 17, 2022

    2.9K
    Translating Ribosome Affinity Purification TRAP to Investigate Arabidopsis thaliana Root Development at a Cell Type-Specific Scale
    09:41

    Translating Ribosome Affinity Purification TRAP to Investigate Arabidopsis thaliana Root Development at a Cell Type-Specific Scale

    Published on: May 14, 2020

    11.7K

    Area of Science:

    • Building Services Engineering
    • Indoor Air Quality Management
    • HVAC System Maintenance

    Background:

    • The Building and Engineering Services Association (B&ES) has revised its TR/19 guidance document.
    • TR/19 specifically addresses the internal cleanliness of ventilation systems.
    • This update is critical for maintaining health and safety standards within buildings.

    Discussion:

    • Richard Norman, Chairman of B&ES's Ventilation Hygiene Group Branch, discusses the recent TR/19 updates.
    • The revisions were necessitated by evolving industry standards and a greater understanding of ventilation hygiene.
    • The importance of regular professional cleaning and maintenance of ventilation systems is emphasized.

    Key Insights:

    • Updated TR/19 guidance provides enhanced protocols for ventilation system cleanliness.
    • The revisions aim to improve indoor air quality and reduce health risks associated with contaminated systems.
    • Specialist cleaning services play a vital role in adhering to the updated standards.

    Outlook:

    • Continued focus on maintaining high standards of ventilation hygiene is expected.
    • Further advancements in cleaning technologies and methodologies may emerge.
    • The updated guidance will likely influence best practices across the HVAC sector.