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Clinical experience with an ethinyl estradiol-desogestrel oral contraceptive
Y Van Trappen1, P Duvivier, M Thiery
1Department of Obstetrics, University Hospital, Gent, Belgium.
Arzneimittel-Forschung
|June 1, 1989
Abstract:
Desogestrel (150 micrograms), a potent progestogen virtually devoid of androgenic activity, was used in combination with 30 micrograms ethinyl estradiol as an oral contraceptive preparation (Marvelon). 219 women completed a total of 4074 cycles, and the use-effectiveness was 0.58 Pearl Units. Serious side effects were not observed. The drug-related discontinuation index was 12.8% in six months.