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Updated: Apr 23, 2026
Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
The survey on implementation of evidence-based nursing in preventing ventilator-associated pneumonia and the effect
1Department of Operation Room, Linyi People's Hospital, Shandong, 276003, China.
Abstract:
The objective is to survey the effect of evidence-based nursing (EBN) in preventing ventilator-associated pneumonia and to observe the effect, providing a reference for clinical nursing intervention. 146 patients with mechanical ventilator were included and randomly divided into control group (n = 73) and observation group (n = 73). Patients in control group received conventional nursing method, and patients in observation group received EBN according to the nursing principles. The questions were raised and the literatures were retrieved to formulate the optimum nursing strategy according to clinical experience and patient need. After nursing, morbidity of VAP in observation group was significantly lower than control group, and length of stay, length of stay in ICU, and the duration of mechanical ventilation were also significantly lower than control group; the differences were statistically significant (P < 0.05). After nursing, the physiological function, physical role, somatic pain, and mental health scores in observation group were significantly higher than control group (P < 0.05). Oral hygiene status in observation group was significantly better than control group; the difference was statistically significant (P < 0.05). After nursing, IL-1, IL-6, and TNF-α in two groups were both decreased (P < 0.05); IL-1, IL-6 and TNF-α in observation group were significantly lower than control group (P < 0.05). When patients were discharged, satisfaction degree in observation group was significantly higher than control group; the difference was statistically significant (P < 0.05). The implementation of EBN can effectively prevent the occurrence of ventilator-associated pneumonia and improve the clinical nursing quality, which is worthy of clinical application.
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