Related Experiment Videos
[Anticarcinogenesis activity of natural carotenes]
H Nishino1, J Takayasu, A Iwashima
1Département de Biochimie, Université Médicale de la Préfecture de Kyoto, Japon.
Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
|January 1, 1989
Abstract:
Natural carotene sample obtained from palm oil was proved to suppress the promoting stage of two-stage carcinogenesis of mouse skin, and also inhibit the proliferation of human malignant tumor cells, such as neuroblastoma GOTO cells, stomach cancer HGC-27 cells, and pancreatic cancer PANC-I cells. Among the major constituents of palm carotene, alpha-carotene showed stronger anti-proliferative effect than beta-carotene. The present results indicate that further investigation for not only beta-carotene but also other kinds of natural carotenes, such as alpha-carotene, should be carried out.