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Early response and induced tolerance to cycloheximide in Neurospora crassa
E Grotewold1, G E Taccioli, G O Aisemberg
1Instituto de Investigaciones en Ingenieria Genética y Biologia Molecular (INGEBI), Buenos Aires, Argentina.
Current Genetics
|June 1, 1989
Abstract:
Incubation of Neurospora crassa mycelia with low doses of cycloheximide induces the expression of several genes. After 6 h in the presence of cycloheximide, mycelia become tolerant to further additions of the drug and the rate of protein synthesis exhibits a lower sensitivity to it. The polypeptide pattern is indicative of a stress situation.